American Society of Human Genetics 2020

Posters by our group

Selected Publications

Note that the titles are links.

• X. Li, Z. Li, H. Zhou, S. M. Gaynor, Y. Liu, H. Chen, R. Sun, R. Dey, D. K. Arnett, S. Aslibekyan, C. M. Ballantyne, L. F. Bielak, J. Blangero, E. Boerwinkle, D. W. Bowden, J. G. Broome, M. P. Conomos, A. Correa, L. A. Cupples, J. E. Curran, B. I. Freedman, X. Guo, G. Hindy, M. R. Irvin, S. L. R. Kardia, S. Kathiresan, A. T. Khan, C. L. Kooperberg, C. C. Laurie, X. S. Liu, M. C. Mahaney, A. W. Manichaikul, L. W. Martin, R. A. Mathias, S. T. McGarvey, B. D. Mitchell, M. E. Montasser, J. E. Moore, A. C. Morrison, J. R. O’Connell, N. D. Palmer, A. Pampana, J. M. Peralta, P. A. Peyser, B. M. Psaty, S. Redline, K. M. Rice, S. S. Rich, J. A. Smith, H. K. Tiwari, M. Y. Tsai, R. S. Vasan, F. F. Wang, D. E. Weeks, Z. Weng, J. G. Wilson, L. R. Yanek, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Lipids Working Group, B. M. Neale, S. R. Sunyaev, G. R. Abecasis, J. I. Rotter, C. J. Willer, G. M. Peloso, P. Natarajan, and X. Lin.
  Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nat Genet, 52(9):969-983, 2020.
• K. J. Arslanian, U. T. Fidow, T. Atanoa, F. Unasa-Apelu, T. Naseri, A. I. Wetzel, A. Pomer, R. L. Duckham, S. T. McGarvey, J. A. Strayer, E. E. Kershaw, D. E. Weeks, and N. L. Hawley.
  A missense variant in CREBRF, rs373863828, is associated with fat-free mass, not fat mass in Samoan infants. Int J Obes (Lond), 2020.
• J. C. Carlson, D. E. Weeks, N. L. Hawley, G. Sun, H. Cheng, T. Naseri, M. S. Reupena, J. Tuitele, R. Deka, S. T. McGarvey, and R. L. Minster.
  Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. J Hum Genet, 2020.
• M. T. Simon, S. S. Eftekharian, S. Ferdinandusse, S. Tang, T. Naseri, M. S. Reupena, S. T. McGarvey, R. L. Minster, D. E. Weeks, L. the Samoan Obesity, G. A. O. S. Group, D. D. Nguyen, S. Lee, K. A. Ellsworth, F. M. Vaz, D. Dimmock, J. Pitt, and J. E. Abdenur.
  A common variant in the short-chain enoyl-CoA hydratase gene ECHS1 contributes to Leigh syndrome in two unrelated families of Samoan descent. Am J Med Genet A, in press.
• H. Sun, M. Lin, E. M. Russell, R. L. Minster, T. F. Chan, T. Naseri, M. S. Reupena, A. Lum-Jones, L. The Samoan Obesity, G. A. O. S. Group, I. Cheng, L. R. Wilkens, L. L. Marchand, C. A. Haiman, and C. W. K. Chiang.
  The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians. bioRxiv [Preprint] May 19, 2020, :https://doi.org/10.1101/2020.05.18.102996, 2020.
• A. A. Thompson, R. L. Duckham, M. M. Desai, C. C. Choy, L. B. Sherar, T. Naseri, C. Soti-Ulberg, M. S. Reupena, A. I. Wetzel, and N. L. Hawley.
  Sex differences in the associations of physical activity and macronutrient intake with child body composition: A cross-sectional study of 3- to 7-year-olds in Samoa. Pediatr Obes, 15(4):e12603, 2020.
• N. R. F. C. (NCD-RisC).
  Repositioning of the global epicentre of non-optimal cholesterol. Nature, 582(7810):73-77, 2020.
• N. L. Hawley, A. Pomer, A. C. Rivara, S. L. Rosenthal, R. L. Duckham, J. C. Carlson, T. Naseri, M. S. Reupena, M. Selu, V. Lupematisila, F. Unasa, L. Vesi, T. Fatu, S. Unasa, K. Faasalele-Savusa, A. I. Wetzel, C. Soti-Ulberg, A. T. Prescott, G. Siufaga, C. Penaia, S. B. To, L. C. LaMonica, V. Lameko, C. C. Choy, S. E. Crouter, S. Redline, R. Deka, E. E. Kershaw, Z. Urban, R. L. Minster, D. E. Weeks, and S. T. McGarvey.
  Exploring the Paradoxical Relationship of a Creb 3 Regulatory Factor Missense Variant With Body Mass Index and Diabetes Among Samoans: Protocol for the Soifua Manuia (Good Health) Observational Cohort Study. JMIR Res Protoc, 9(7):e17329, 2020.
• D. N. Harris, M. D. Kessler, A. C. Shetty, D. E. Weeks, R. L. Minster, S. Browning, E. E. Cochrane, R. Deka, N. L. Hawley, M. S. Reupena, T. Naseri, T.-O. for Precision Medicine Consortium, T. P. G. W. Group, S. T. McGarvey, and T. D. O’Connor.
  Evolutionary history of modern Samoans. Proc Natl Acad Sci U S A, 117(17):9458-9465, 2020.
• S. B. To, A. A. Brewis, A. Pomer, T. Naseri, M. S. Reupena, S. T. McGarvey, and N. L. Hawley.
  Changing body norms in the context of increasing body size: Samoa in 1995 and 2018. Am J Hum Biol, :e23395, 2020.
• C. C. Choy, N. L. Hawley, T. Naseri, M. S. Reupena, and S. T. McGarvey.
  Associations between socioeconomic resources and adiposity traits in adults: Evidence from Samoa. SSM Popul Health, 10:100556, 2020.
• J. J. Jiang, S. M. Reupena, T. Naseri, R. M. Swift, J. E. McGeary, and S. T. McGarvey.
  Alcohol Consumption among Samoan Adults in 2010: Patterns, Correlates and Health Implications. Alcohol Alcohol, 55(6):681-689, 2020.
• J. C. Carlson, S. L. Rosenthal, E. M. Russell, N. L. Hawley, G. Sun, H. Cheng, T. Naseri, M. S. Reupena, J. Tuitele, R. Deka, S. T. McGarvey, D. E. Weeks, and R. L. Minster.
  A missense variant in CREBRF is associated with taller stature in Samoans. Am J Hum Biol, :e23414, 2020.
• A. C. Adia, N. L. Hawley, T. Naseri, M. S. Reupena, and S. T. McGarvey.
  Tobacco smoking patterns in Samoa in 2010: Implications for interventions. Tob Prev Cessat, 5:50, 2019.
• D. Taliun, D. Harris, M. Kessler, J. Carlson, Z. Szpiech, R. Torres, S. G. Taliun, A. Corvelo, S. Gogarten, H. M. Kang, A. Pitsillides, J. LeFaive, S.-b. Lee, X. Tian, B. Browning, S. Das, A.-K. Emde, W. Clarke, D. Loesch, A. Shetty, T. Blackwell, Q. Wong, F. Aguet, C. Albert, A. Alonso, K. Ardlie, S. Aslibekyan, P. Auer, J. Barnard, G. Barr, L. Becker, R. Beer, E. Benjamin, L. Bielak, J. Blangero, M. Boehnke, D. Bowden, J. Brody, E. Burchard, B. Cade, J. Casella, B. Chalazan, Y.-D. I. Chen, M. Cho, S. H. Choi, M. Chung, C. Clish, A. Correa, J. Curran, B. Custer, D. Darbar, M. Daya, M. d. Andrade, D. DeMeo, S. Dutcher, P. Ellinor, L. Emery, D. Fatkin, L. Forer, M. Fornage, N. Franceschini, C. Fuchsberger, S. Fullerton, S. Germer, M. Gladwin, D. Gottlieb, X. Guo, M. Hall, J. He, N. Heard-Costa, S. Heckbert, M. Irvin, J. Johnsen, A. Johnson, S. L. R. Kardia, T. Kelly, S. Kelly, E. Kenny, D. Kiel, R. Klemmer, B. Konkle, C. Kooperberg, A. Köttgen, L. Lange, J. Lasky-Su, D. Levy, X. Lin, K.-H. Lin, C. Liu, R. J. F. Loos, L. Garman, R. Gerszten, S. Lubitz, K. Lunetta, A. C. Y. Mak, A. Manichaikul, A. Manning, R. Mathias, D. McManus, S. McGarvey, and others.
  Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. bioRxiv [Preprint] March 06, 2019, :https://doi.org/10.1101/563866, 2019.
• N. C. D. Risk Factor Collaboration.
  Rising rural body-mass index is the main driver of the global obesity epidemic in adults. Nature, 569(7755):260-264, 2019.
• M. Taub, J. Weinstock, K. Iyer, L. Yanek, M. Conomos, J. Brody, A. Keramati, C. Laurie, M. Arvanitis, A. Smith, J. Lane, L. Becker, J. Bis, J. Blangero, E. Bleecker, E. Burchard, J. Celedon, Y. P. Chang, B. Custer, D. Darbar, L. de las Fuentes, D. DeMeo, B. Freedman, M. Garrett, M. Gladwin, S. Heckbert, B. Hidalgo, C. Ingram, M. Irvin, W. Craig Johnson, S. Kaab, L. Launer, J. Lee, S. Liu, A. Moscati, K. North, P. Peyser, N. Rafaels, L. Raffield, D. Weeks, M. Wheeler, L. Keoki Williams, W. Zhao, M. Armanios, S. Aslibekyan, P. Auer, D. Bowden, B. Cade, I. Yii-Der Chen, M. Cho, A. Cupples, J. Curran, M. Daya, R. Deka, X. Guo, L. Hou, S.-J. Hwang, J. Johnsen, E. Kenny, A. Levin, C. Liu, R. Minster, M. Nouraie, E. Sabino, J. Smith, N. Smith, J. Lasky Su, M. Telen, H. Tiwari, R. Tracy, M. White, Y. Zhang, K. Wiggins, S. Weiss, R. Vasan, K. Taylor, M. Sinner, E. Silverman, M. Benjamin Shoemaker, W. H. H. Sheu, J. Rotter, S. Redline, B. Psaty, J. Peralta, N. Palmer, R. J. F. Loos, C. Montgomery, B. Mitchell, D. Meyers, S. McGarvey, A. C. Y. Mak, R. Kumar, C. Kooperberg, B. Konkle, S. Kelly, S. L. R. Kardia, R. Kaplan, J. He, H. Gui, M. Fornage, and others.
  Novel genetic determinants of telomere length from a multi-ethnic analysis of 75,000 whole genome sequences in TOPMed. bioRxiv [Preprint] September 04, 2019, :https://doi.org/10.1101/749010, 2019.
• A. Bick, J. Weinstock, S. Nandakumar, C. Fulco, M. Leventhal, E. Bao, J. Nasser, S. Zekavat, M. Szeto, C. Laurie, M. Taub, B. Mitchell, K. Barnes, A. Moscati, M. Fornage, S. Redline, B. Psaty, E. Silverman, S. Weiss, N. Palmer, R. Vasan, E. Burchard, S. L. R. Kardia, J. He, R. Kaplan, N. Smith, D. Arnett, D. Schwartz, A. Correa, M. de Andrade, X. Guo, B. Konkle, B. Custer, J. Peralta, H. Gui, D. Meyers, S. McGarvey, I. Y.-D. Chen, B. Shoemaker, P. Peyser, J. Broome, S. Gogarten, F. F. Wang, Q. Wong, M. Montasser, M. Daya, E. Kenny, K. North, L. Launer, B. Cade, J. Bis, M. Cho, J. Lasky-Su, D. Bowden, A. Cupples, A. C. Y. Mak, L. Becker, J. Smith, T. Kelly, S. Aslibekyan, S. Heckbert, H. Tiwari, I. Yang, J. Heit, S. Lubitz, S. Rich, J. Johnsen, J. Curran, S. Wenzel, D. Weeks, D. Rao, D. Darbar, J.-Y. Moon, R. Tracy, E. Buth, N. Rafaels, R. J. F. Loos, L. Hou, J. Lee, P. Kachroo, B. Freedman, D. Levy, L. Bielak, J. Hixson, J. Floyd, E. Whitsel, P. Ellinor, M. Irvin, T. Fingerlin, L. Raffield, S. Armasu, J. Rotter, M. Wheeler, E. Sabino, J. Blangero, K. Williams, B. Levy, W. H.-H. Sheu, D. Roden, E. Boerwinkle, and others.
  Inherited Causes of Clonal Hematopoiesis of Indeterminate Potential in TOPMed Whole Genomes. bioRxiv [Preprint] September 27, 2019, :https://doi.org/10.1101/782748, 2019.
• J. C. Carlson, D. E. Weeks, N. L. Hawley, G. Gao, H. Cheng, T. Naseri, M. S. Reupena, R. Deka, S. T. McGarvey, and R. L. Minster.
  Genome-wide association studies in Samoans give insight into the genetic architecture of fasting serum lipid levels. bioRxiv [Preprint] June 06, 2019, :https://doi.org/10.1101/411546, 2019.
• H. Maredia, N. L. Hawley, G. Lambert-Messerlian, U. Fidow, M. S. Reupena, T. Naseri, and S. T. McGarvey.
  Reproductive health, obesity, and cardiometabolic risk factors among Samoan women. Am J Hum Biol, 30(3):e23106, 2018.
• T. J. Major, M. Krishnan, R. K. Topless, O. Dewes, J. Thompson, J. Zoysa, L. K. Stamp, N. Dalbeth, R. Deka, D. E. Weeks, R. L. Minster, P. Wilcox, D. Grattan, P. R. Shepherd, A. N. Shelling, R. Murphy, and T. R. Merriman.
  Re: “Widespread prevalence of a CREBRF variant amongst Māori and Pacific children is associated with weight and height in early childhood”. Int J Obes (Lond), 42(7):1389-1391, 2018.
• M. Krishnan, T. J. Major, R. K. Topless, O. Dewes, L. Yu, J. M. D. Thompson, L. McCowan, J. de Zoysa, L. K. Stamp, N. Dalbeth, J. Harre Hindmarsh, N. Rapana, R. Deka, W. W. H. Eng, D. E. Weeks, R. L. Minster, S. T. McGarvey, S. Viali, T. Naseri, M. Sefuiva Reupena, P. Wilcox, D. Grattan, P. R. Shepherd, A. N. Shelling, R. Murphy, and T. R. Merriman.
  Discordant association of the CREBRF rs373863828 A allele with increased BMI and protection from type 2 diabetes in Maori and Pacific (Polynesian) people living in Aotearoa/New Zealand. Diabetologia, 61(7):1603-1613, 2018.
• P. Natarajan, G. M. Peloso, S. M. Zekavat, M. Montasser, A. Ganna, M. Chaffin, A. V. Khera, W. Zhou, J. M. Bloom, J. M. Engreitz, J. Ernst, J. R. O’Connell, S. E. Ruotsalainen, M. Alver, A. Manichaikul, W. C. Johnson, J. A. Perry, T. Poterba, C. Seed, I. L. Surakka, T. Esko, S. Ripatti, V. Salomaa, A. Correa, R. S. Vasan, M. Kellis, B. M. Neale, E. S. Lander, G. Abecasis, B. Mitchell, S. S. Rich, J. G. Wilson, L. A. Cupples, J. I. Rotter, C. J. Willer, S. Kathiresan, and N. T. L. W. Group.
  Deep-coverage whole genome sequences and blood lipids among 16,324 individuals. Nat Commun, 9(1):3391, 2018.
• S. M. Zekavat, S. Ruotsalainen, R. E. Handsaker, M. Alver, J. Bloom, T. Poterba, C. Seed, J. Ernst, M. Chaffin, J. Engreitz, G. M. Peloso, A. Manichaikul, C. Yang, K. A. Ryan, M. Fu, W. C. Johnson, M. Tsai, M. Budoff, R. S. Vasan, L. A. Cupples, J. I. Rotter, S. S. Rich, W. Post, B. D. Mitchell, A. Correa, A. Metspalu, J. G. Wilson, V. Salomaa, M. Kellis, M. J. Daly, B. M. Neale, S. McCarroll, I. Surakka, T. Esko, A. Ganna, S. Ripatti, S. Kathiresan, P. Natarajan, and N. T. L. W. Group.
  Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. Nat Commun, 9(1):2606, 2018.
• N. C. D. R. F. Collaboration.
  Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants. Int J Epidemiol, 47(3):872-883i, 2018.
• C. Linhart, T. Naseri, S. Lin, R. Taylor, S. Morrell, S. T. McGarvey, D. J. Magliano, and P. Zimmet.
  Continued increases in blood pressure over two decades in Samoa (1991-2013); around one-third of the increase explained by rising obesity levels. BMC Public Health, 18(1):1122, 2018.
• N. C. D. R. F. Collaboration.
  Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet, 390(10113):2627-2642, 2017.
• N. C. D. R. F. Collaboration.
  Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants. Lancet, 389(10064):37-55, 2017.
• S. Lin, T. Naseri, C. Linhart, S. Morrell, R. Taylor, S. T. McGarvey, D. J. Magliano, and P. Zimmet.
  Trends in diabetes and obesity in Samoa over 35 years, 1978-2013. Diabet Med, 34(5):654-661, 2017.
• C. Linhart, T. Naseri, S. Lin, R. Taylor, S. Morrell, S. T. McGarvey, D. J. Magliano, and P. Zimmet.
  Tobacco smoking trends in Samoa over four decades: can continued globalization rectify that which it has wrought?. Global Health, 13(1):31, 2017.
• D. Wang, N. L. Hawley, A. A. Thompson, V. Lameko, M. S. Reupena, S. T. McGarvey, and A. Baylin.
  Dietary Patterns Are Associated with Metabolic Outcomes among Adult Samoans in a Cross-Sectional Study. J Nutr, 147(4):628-635, 2017.
• S. Lin, T. Naseri, C. Linhart, S. Morrell, R. Taylor, S. T. McGarvey, D. J. Magliano, and P. Zimmet.
  Diabetes incidence and projections from prevalence surveys in Samoa over 1978-2013. Int J Public Health, 62(6):687-694, 2017.
• N. C. D. R. F. Collaboration.
  Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4.4 million participants. The Lancet, 387(10027):1513-1530, 2016.
• H. Maredia, G. M. Lambert-Messerlian, G. E. Palomaki, S. Viali, N. L. Hawley, and S. T. McGarvey.
  Cut-off levels for hyperandrogenemia among Samoan women: An improved methodology for deriving normative data in an obese population. Clin Biochem, 49(10-11):782-6, 2016.
• N. C. D. R. F. Collaboration.
  A century of trends in adult human height. Elife, 52016.